Urinalysis by means of Test Strips

Consequences of inappropriate urine specimen storage

Until analysis, urine should be protected from direct sunlight, thus avoiding the possibility of erroneous results due to subsequent urine changes. In case of prolonged urine storage beyond the above mentioned time limits, the following changes develop:
• bilirubin - decreased due to sun exposure
• color - changed due to oxidation or metabolite reduction
• bacterial count - increased
• cell and cylinder count - decreased due to disintegration, especially in a diluted or alkaline specimen
• glucose - decreased due to glycolysis and bacterial utilization
• ketones - decreased due to volatilization
• nitrites - increased due to bacterial reduction of nitrates
• pH - increased because of urea decomposition to ammonia due to the bacterial urease activities
• turbidity - increased due to bacterial growth and possible deposition of amorphous salts
• urobilinogen - decreased due to oxidation to urobilin
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